Endocrine Abstracts

Introduction: Insulinomas are rare pancreatic islet cell tumours with an incidence of four cases per million per year. About 10% of all insulinomas are malignant. We here examined an insulinoma with aggressive driving in a young male patient with severe hypoglycaemia in the emergency room.Case report: 34-year-old male patient was admitted to the emergency department with the blurring of consciousness. Blood glucose was 19 mg/dl, consciousness tends to sl...

Background: Metastases to the pituitary gland are rare events and usually indicate widespread malignant disease. Most common symptoms of pituitary metastases are diabetes insipidus and visual disturbances. The lung and breast are the most common sites of primary tumors that metastasize to the pituitary gland. Pituitary metastasis of gastrointestinal tractus is extremely rare.Case presentation: A 53-year-old woman was given chemotherapy for colon cancer w...

Aim: In our study; we aimed to evaluate the relationship between Ankle-brachial index (ABI) values and diabetes duration, and macrovascular complications in patients with DM with demographic data, anthropometric measurements, as well as clinical and laboratory data.Materials and methods: Our study is a cross-sectional study of 226 randomly selected DM patients who were admitted to the diabetes outpatient clinic of our hospital between April 2019 and Octo...

Ectopic ACTH syndrome (EAS) occurs in around 10% of all cases with ACTH-dependent hypercortisolism. The mean age of clinical presentation varies from 45 to 50 years, and most of them caused by intrathoracic neoplasm, and recognition of the disorder may be delay. Subsequently, it may be difficult to locate the ACTH source and manage the patients’ hypercortisolism. We present our patients with EAS from 2000 to 2007. Four patients, aged 15–43 years, two females and two ...

Pheochromocytomas are tumors capable of producing catecholamines and a variety of biologically active resulting in unusual clinical manifestations. We report the case of 18-year-old female with pheochromocytoma exhibiting fever of unknown origin. She had experienced continuous fever (ranging between 37.1–41  °C) and chills for previous several weeks. Antipyretics had been ineffective in lowering the body temperature and she was referred to our hospital when an a...

Introduction: We report a case of paraganglioma of glomus caroticum with lung metastases treated with 150 mCi 131I-MIBG.Case: A 25-year-old woman was referred to our department for cachexia. She had low BMI (18) normotension, mild normochromic normocytic anemia with a mass under left mandibula. Radiologic imaging of neck revealed that 24×36×45 mm diameter mass surrounding of carotis externa and interna at the level of bifurcation. She underwent...

Introduction: We designed a retrospective study to investigate the clinical presentation, laboratory and pathological findings of 14 patients with ACTH-independent macronodular adrenal hyperplasia.Materials and methods: Diagnose of Cushing’ s syndrome was confirmed by biochemical tests, adrenal hyperplasia was confirmed by pathological examination in all patients.Results: No supression was observed in overnight, low and high d...

Aim: The ankle-brachial index (ABI) shows the existence of peripheral arterial disease and is also related to cardiovascular mortality in diabetic patients, even in those with coronary artery disease at an early stage. Normal levels are considered to be an ABI of 0.9 – 1.3; ABI thresholds of less than 0.9 and more than 1.3 are highly suspicious for PAD and high CV risk in diabetic patients. In this study, we planned to investigate the ankle-brachial index values in diabet...

Aim: Autonomic cortisol secretion (ACS) is a clinical picture without overt signs of Cushing’s Syndrome despite adrenal adenoma and ACTH-independent cortisol secretion. These patients, who currently do not have a standard treatment, are followed up, especially for known comorbidities of hypercortisolemia such as obesity, diabetes mellitus (DM), hypertension, osteoporosis, and hyperlipidemia. However, it remains unclear how long the patients will be followed and when the t...

Background: Obesity is one of the most critical problems nowadays, its frequency and consequences. Since the risk of morbidity and mortality increases in obese individuals, lifestyle changes, pharmacotherapy, and bariatric surgery (BS) methods are used for treatment. BS is generally considered the most effective method to treat morbid obesity. However, it is known that thyroid function has a role in weight regulation, the effect of preoperative thyroid function on weight loss ...